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R & D Infrastructure
Overview
Cohizon Life Sciences’ R&D infrastructure is focused on agrochemical process development, process optimization, and seamless scale-up from laboratory development to commercial manufacturing. Strategically located in Rabale, Navi Mumbai and Ankleshwar, Gujarat, the R&D centers integrate synthesis, flow chemistry, fluorination, analytical, and process safety capabilities to support technology transfer and plant operations across complex chemical processes. Spanning over 54,000 sq. ft. of laboratory and research space, Cohizon’s R&D team comprises 85+ scientists, including 12 PhD and 55 master's degree holders, supporting development across specialized chemistries and scalable process platforms.
Our Dedicated R&D Labs
Rabale, Navi Mumbai, India
State-of-the-art Research & Development Centre
Commenced operations in December 2023
5000+ m² research infrastructure
Focused on process development, optimization, and scale-up
Advanced Laboratory Capabilities
Dedicated synthesis laboratories supporting diverse synthetic methodologies and reaction screening.
- ◆4 dedicated synthesis labs
- ◆48 fume hoods ensuring safe and controlled experimental conditions
- ◆Rotary evaporators (Rotavapors)
- ◆Combi Flash Chromatography Systems (Combi flashes)
- ◆Precise dosing pumps
- ◆Mya4 (Parallel Synthesizers) for efficient reaction screening
- ◆Laboratory centrifuges
- ◆Photo reactors for light-sensitive reactions
Dedicated infrastructure for hazard identification, risk assessment, and process control studies.
- ◆Differential Scanning Calorimetry (DSC) for screening thermal hazards
- ◆Accelerating Rate Calorimeter (ARC) to identify safe and unsafe conditions of handling thermally active chemicals
- ◆Reaction Calorimeter (RC) for understanding the heat of reaction and the desired level of process control requirement
- ◆Automated Jacketed Reactors for identifying standard operating conditions useful in designing process control
- ◆Distillation Columns for fractionation of volatile components
- ◆Vapor–liquid equilibrium (VLE) Apparatus to determine VLE, useful in designing distillation columns
Pilot-scale facility for taking validated processes to kilogram-scale production.
- ◆Reactors – 20 Nos., 500L to 2KL, SS, MS GLR & Hastelloy
- ◆Hydrogenator – 1 No.
- ◆APND – 2 Nos.
- ◆RVPD – 1 No.
- ◆Centrifuge – 2 Nos.
- ◆DCS and automation
- ◆Dedicated utilities: cooling water, chilled water, chilled brine (-15°C & -35°C)
- ◆Wide temperature range from -30°C to 240°C
SCADA-operated kilo labs with automation and integrated data loggers for precise process control and data acquisition.
- ◆2 dedicated in-house kilo labs (Herbicide & Non-Herbicide)
- ◆Glass reactor setup available with different types of agitators ~ 30L, 50L & 100L
- ◆Packed Distillation Columns for efficient purification at larger scales
- ◆Agitated Nutsche Filter Dryers (ANFDs) in Glass, Stainless Steel (SS), and Hastelloy/Carbon steel (H/C)
- ◆Centrifuge for solid-liquid separation
- ◆Vacuum tray dryer
- ◆Short Path Distillation Unit (SPDU)
- ◆20L Rotary Evaporator for solvent recovery at kilo scale
- ◆Capable of handling high-viscosity products
- ◆All reactors are designed to operate over a wide temperature range from -30°C to 240°C
- ◆Efficient high-temperature, high-vacuum distillation setup for separating close-boiling components
Dedicated laboratory infrastructure for high-pressure and fluorination chemistry.
- ◆6 high-pressure reactors constructed with Stainless Steel (SS) and Hastelloy/Carbon steel (H/C) for material compatibility and safety
- ◆Capability for High-Pressure Hydrogenation
- ◆2 dedicated workstations with specialized safety features for reactions involving Anhydrous Hydrogen Fluoride (AHF)
- ◆High-pressure parallel synthesizer (Polyblock) for rapid catalyst and reaction condition optimization
- ◆PLC operated for precise process control and enhanced safety in high-pressure reactions
Development of cost-effective processes through flow chemistry.
- ◆Corning – G1 Reactor
- ◆Vapourtech – R4 series reactor and photoreactor
- ◆ACR-ATR-AM (Automated Continuous Reactor – Advanced Technology Reactor – Automated Modular) technology
- ◆Continuous Stirred Tank Reactor (CSTR)
- ◆Static Mixers for efficient mixing in continuous flow
- ◆Membrane Separation technology for continuous separation and purification
Central analytical services supporting quality control, research support, and data generation.
- ◆Gas Chromatography (GC) Systems
- ◆Liquid Chromatography-Mass Spectrometry (LCMS)
- ◆Gas Chromatography-Mass Spectrometry-Headspace (GCMS-HS)
- ◆Evaporative Light Scattering Detector (ELSD)
- ◆Refractive Index (RI) and Fluorescence Detectors
- ◆Ultra-Performance Liquid Chromatography (UPLC)
- ◆UV-Vis Spectrophotometer
- ◆Infrared (IR) Spectroscope
- ◆Ion Chromatography
- ◆Nuclear Magnetic Resonance (NMR) Spectrometer
- ◆Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
- ◆Atomic Absorption Spectroscopy (AAS)
- ◆Preparative High-Performance Liquid Chromatography (Preparative HPLC)
